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Juvenile amyotrophic lateral sclerosis

3 OMIM references -
4 associated genes
12 signs/symptoms

COMMON GENES: 1

Myxoid/round cell liposarcoma

1 OMIM reference -
2 associated genes
4 signs/symptoms

Juvenile amyotrophic lateral sclerosis

Myxoid/round cell liposarcoma

ALS2	(UniProt - OMIM)		DDIT3	(UniProt - OMIM)
FUS	(UniProt - OMIM)		FUS	(UniProt - OMIM)
SIGMAR1	(UniProt - OMIM)
SPG11	(UniProt - OMIM)


COMMON GENES	FUS

Citations in the biomedical literature:

Juvenile amyotrophic lateral sclerosis		Myxoid/round cell liposarcoma
	Synonym(s): - JALS - Juvenile Charcot disease - Juvenile Lou Gehrig disease		Synonym(s): - MRCLS

	Classification (Orphanet): - Rare genetic disease - Rare neurologic disease		Classification (Orphanet): - Rare oncologic disease

	Classification (ICD10): - Diseases of the nervous system -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: adult Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic

	External references: 3 OMIM references - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D018208

Juvenile amyotrophic lateral sclerosis		Myxoid/round cell liposarcoma
	Very frequent - Abnormal EMG / electromyogram / electropmyography - Abnormal gait - Autosomal recessive inheritance - Elocution disorders / dysarthria / dysphonia - Hypereflexia - Hypertonia / spasticity / rigidity / stiffness - Motor deficit / trouble - Pyramidal syndrome Frequent - Muscle hypotrophy / atrophy / dystrophy / agenesis / amyotrophy - Pseudobulbar signs / spasmodic laugh and cry Occasional - Bladder and ureter anomalies - Sensitive trouble / deficit		Very frequent - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling Occasional - Acute abdominal pain / colic - Intestinal transit disorder